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In suppressive treatment, chloroquine inhibits the erythrocytic stage of development of plasmodia {01} {02} {06} {29}. Therefore, mefloquine may be considered for prophylactic use in women who are pregnant or likely to become pregnant when exposure to chloroquine-resistant P. The combination of chloroquine and proguanil for sub-Saharan Africa has lower efficacy than other regimens {41}. Weekly mefloquine is recommended for most travelers to areas with chloroquine-resistant Plasmodium falciparum {36}. Chloroquine is excreted very slowly and may persist in urine for months or years after medication is discontinued {09} {15}. So visit the website and type chloroquine in the top left search box.

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